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Clinical Research

Miracle berries and their active substance, miraculin, have both been thoroughly used in clinical research with positive results. We have posted a sampling of the available research here, and we invite you to keep an eye on this page for more articles coming soon.

Cancer Related Research

a doctor and a patient smiling
  1. “Efficacy and Safety of Habitual Consumption of a Food Supplement Containing Miraculin in Malnourished Cancer Patients: the CLINMIR Pilot Study” From Research Gate
  2. The regular consumption of a food supplement containing miraculin can contribute to reducing biomarkers of inflammation and cachexia in malnourished patients with cancer and taste disorders. From Research Gate
  3. Effects of novel food rich in miraculin on the intestinal microbiome of malnourished patients with cancer and dysgeusia From Research Gate
  4. Effects of novel food rich in miraculin on the oral microbiome of malnourished oncologic patients with dysgeusia From Research Gate
  5. “Miracle Berry as a Potential Supplement in the Control of Metabolic Risk Factors in Cancer” From National Library of Medicine
  6. “Synsepalum dulcificum extracts exhibit cytotoxic activity on human colorectal cancer cells and upregulate c-fos and c-jun early apoptotic gene expression” From Research Gate
  7. “Effect of Regular Consumption of a Miraculin-Based Food Supplement on Taste Perception and Nutritional Status in Malnourished Cancer Patients: the CLINMIR Pilot Study” From MedRxiv
  8. “Anti-Angiogenesis and Anticancer Activities”: From Research Gate
  9. “Evaluation of the antimicrobial and anticancer properties of the fruits of Synsepalum dulcificum (Sapotaceae)” From Tropical Journal of Pharmaceutical Research
  10. “Biological Activities of Miracle Berry Supercritical Extracts as Metabolic Regulators in Chronic Diseases” From National Library of Medicine
  11. “Treatment of Taste Alterations in Chemotherapy Patients Using the ‘Miracle Fruit’”: Preliminary Analysis of a Pilot Study.” American Society of Clinical Oncology (ASCO) From ASCO Publications
  12. “Pilot Study of ‘Miracle Fruit’ to Improve Food Palatability for Patients Receiving Chemotherapy.” U.S. From National Library of Medicine National Institutes of Health
  13. The Effects of Taste Changes on the Quality of Life of Patients From Academia.Edu

Diabetes Related Research

man being finger pricked in doctor’s office
  1. “Anti-Diabetic Properties of Synsepalum dulcificum and Its Potential Inclusion in Functional Yogurt” From Research Gate
  2. “Improvement of Insulin Resistance by Miracle Fruit (Synsepalum dulcificum) in Fructose-Rich Chow-Fed Rats.” U.S. National Library of Medicine National Institutes of Health From National Library of Medicine
  3. Modulatory Effects of Miracle Fruit Ethanolic Extracts on Glucose Uptake Through the Insulin Signaling Pathway in C2C12 Mouse Myotubes Cells” From National Library of Medicine
  4. “Antihyperglycemic and hepatoprotective properties of miracle fruit (Synsepalum dulcificum) compared to aspartame in alloxan-induced diabetic mice” From Research Gate
  5. “Anti-Diabetic Effect of the Leaf Extracts of the Miracle Berry” From National Library of Medicine
  6. “Antidiabetic Potential of the Leaf Extract of Miracle Berry Plant in Type 2 Diabetes” From National Library of Medicine

Alzheimers Dementia Related Research

  1. “Miracle fruit seed as a potential supplement for the treatment of learning and memory disorders in Alzheimer’s disease” From National Library of Medicine
  2. “Inhibition of CXCR4: A perspective on miracle fruit seed for Alzheimer’s disease treatment” From Science Direct

As a Taste Modifier

a strawberry fruit smoothie with berries all around it
  1. “Taste Modification for Novel Foods” From Research Gate
  2. “Positive improvement in palatability of metabolic formula with the use of miraculin protein in patients with inborn errors of metabolism and healthy adults” From SciElo
  3. “The Miracle Berry and Miraculin: A Review” From Miracle Berry and Miraculin
  4. “The Miracle Fruit: An Undergraduate Laboratory Exercise in Taste Sensation and Perception”: From National Library of Medicine

Phytochemicals, Nutritionals, and Antioxidant Properties of the Miracle Berry

colorful miracle berries on a bush
  1. “Chemical Constituents and Their Antioxidant Activities”: From Research Gate
  2. “Physicochemical Characterisation of Polysaccharides from the Seeds and Leaves of Miracle Fruit (Synsepalum dulcificum) and Their Antioxidant and α -Glucosidase Inhibitory Activities In Vitro” From Research Gate 
  3. “Phytochemicals, Nutritionals, and Antioxidant Properties of the Miracle Berry” From Research Gate
  4. “Phytochemicals, Antinutrient, and Amino Acid Composition of the Miracle Berry” From IOSR Journal of Pharmacy and Biological Sciences
  5. “Amino Acid Profile and Oxidazable Vitamin Content of Miracle Fruit” From Wiley Online Library
  6. “Proximate and Micronutrient Analysis of Miracle Fruit” From Academia.Edu
  7. “Potential Nutritional Values of Skin, Pulp, and Seed of the Miracle Fruit” From Semantic Scholar
  8. “Proximate, Anti-Nutritional, and Phytochemical Composition of the Yellow Variety of the Miracle Fruit” From Research Gate
  9. “Nutritionals, Anti-Nutritional, and Phytochemical Profile of the Leaves and Fruit of the Miracle Fruit” From American Journal of Biological Chemistry
  10. “Contents of Phenolics and Flavonoids and Antioxidant Activities in Skin, Pulp, and Seeds of Miracle Fruit.” U.S. National Library of Medicine National Institutes of Health From National Library of Medicine
  11. “Antioxidant-Rich Phytochemicals in Miracle Berry (Synsepalum dulcificum) and Antioxidant Activity of Its Extracts.” U.S. National Library of Medicine National Institutes of Health From National Library of Medicine

Toxicology Analysis of the Miracle Berry

miracle berries up close
  1. “Effects of Methanol Extract of Synsepalum Dulcificum Pulp on Some Biochemical Parameters in Albino Rats”: From Academic Journals
  2. “Effect of Synsepalum Dulcificum Extract on Oxidative Stress and Hepatotoxicity Indices” From FUTA Journal of Research in Sciences

Non-Allergic Properties 

a logo that reads “Allergen-Free"

“Discarded Cross-Allergy Between Miracle Berry (Synsepalum dulcificum) and Peanut” From Research Gate

Other Health Benefits of the Miracle Berry

woman smiling while holding glass of juice
  1. “Nutritional Benefits, Phytochemical Constituents, Ethnomedical Uses, and Biological Properties of the Miracle Fruit Plant”: From Research Gate
  2. “Influence of Miracle Berry Extract and Microencapsulated Lactococcus on the Antioxidant Activity and Probiotic Viability of Functional Yogurt” From Research Gate
  3. “Anti-Hyperuricaemic Effect of Miracle Berry – Ability of the Miracle Berry to Reduce Uric Acid in the Blood” From National Library of Medicine

Who We Are

Since 2014, MiraBurst, founded by Dr. Emmanuel Asare, has proudly offered the world’s leading natural taste-modifying and taste-masking superfruit: the miracle berry. Whether you are a cancer survivor, cancer patient undergoing chemotherapy with or without taste-disturbances, diabetic or prediabetic, you can now enjoy all the health benefits of this unique superfruit in the form of our trademarked MiraBurst Mini Squares. Order today!

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