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Clinical Research

Miracle Berries and their active ingredient, miraculin, have both been subjected to clinical research with positive results. We post a sampling of the available research here. We invite you to keep an eye on this page for more articles soon.



As a Taste Modifier:



“The Miracle Berry and Miraculin: A Review”
http://miracleberryandmiraculin.wordpress.com/2014/07/27/the-miracle-berry-and-miraculin-a-review/


“The Miracle Fruit: An Undergraduate Laboratory Exercise in Taste Sensation and Perception”
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105965/



For Chemotherapy Taste Improvement:



Treatment of taste alterations in chemotherapy patients using the “miracle fruit”: Preliminary analysis of a pilot study. American Society of Clinical Oncology (ASCO):  http://meetinglibrary.asco.org/content/51247-74


Synsepalum dulcificum Memorial Sloan Kettering Cancer:  http://www.mskcc.org/cancer-care/herb/synsepalum-dulcificum


Pilot study of “miracle fruit” to improve food palatability for patients receiving chemotherapy. U.S. National Library of Medicine National Institutes of Health: http://www.ncbi.nlm.nih.gov/pubmed/23022943



Diabetic Uses:



Improvement of insulin resistance by miracle fruit (Synsepalum dulcificum) in fructose-rich chow-fed rats. U.S. National Library of Medicine National Institutes of Health:  http://www.ncbi.nlm.nih.gov/pubmed/16941611


Anti-Diabetic effect of the leaf extracts of the miracle berry:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747512/
Antidiabetic potential of the leaf extract of miracle berry plant in type 2 diabetes:
https://www.ncbi.nlm.nih.gov/pubmed/31374224
Modulatory effects of miracle fruit ethanolic extracts on glucose uptake through the insulin signaling pathway in C2C12 mouse myotubes cells
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418466/  



Phytochemicals, Nutritionals and Antioxidant Properties of the Miracle Berry


Phytochemicals, Nutritionals and Antioxidant Properties of the Miracle Berry:



https://www.researchgate.net/publication/299418843_Phytochemicals_nutritionals_and_antioxidant_properties_of_miracle_fruit_Synsepalum_dulcificum


Phytochemicals, Antinutrient and Amino Acid Composition of the Miracle Berry:

http://www.iosrjournals.org/iosr-jpbs/papers/Vol9-issue2/Version-5/E09252529.pdf


Amino Acid Profile and Oxidazable Vitamin content of Miracle Fruit:

https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.213


Proximate and Micronutrient Analysis of Miracle Fruit:

https://www.academia.edu/7914076/PROXIMATE_AND_MICRONUTRIENT_ANALYSES_OF_SYNSEPALUM_DULCIFICUM_PULP


Potential Nutritional Values of Skin, Pulp and Seed of the Miracle Fruit:

https://pdfs.semanticscholar.org/5ce4/919e7543d26bb35665fcf6dae1b265bdeafb.pdf


Proximate, Anti-Nutritional and Phytochemical Composition of the Yellow Variety of the Miracle Fruit:

https://pdfs.semanticscholar.org/7d05/1a745a8d812f4b0ab641409a1634a0b0cc51.pdf

Nutritionals, Anti-Nutritional and Phytochemical Profile of the Leaves and Fruit of the Miracle Fruit:

https://miraburst.com/wp-content/uploads/2020/01/Nutritionals-Anti-Nutritional-and-Phytochemical-Profile-of-the-Leaves-and-Fruit-of-the-Miracle-Fruit.pdf


Contents of phenolics and flavonoids and antioxidant activities in skin, pulp, and seeds of miracle fruit.


U.S. National Library of Medicine National Institutes of Health:
http://www.ncbi.nlm.nih.gov/pubmed/21535817


Antioxidant-rich phytochemicals in miracle berry (Synsepalum dulcificum) and antioxidant activity of its extracts


U.S. National Library of Medicine National Institutes of Health:
http://www.ncbi.nlm.nih.gov/pubmed/24491731



Other Health Benefits of the Miracle Berry:



Cytotoxic (anticancer) effect of miracle berry on human colorectal cancer cells.


http://www.apjtb.org/article.asp?issn=2221-1691;year=2018;volume=8;issue=3;spage=173;epage=178;aulast=Seong


Anti-hyperuricaemic effect of miracle berry – Ability of the miracle berry to reduce uric acid in the blood.


https://www.ncbi.nlm.nih.gov/pubmed/26821007



Toxicology Analysis of the Miracle Berry:



Effects of Methanol Extract of Synsepalum Dulcificum Pulp on some biochemical parameters in albino rats:

https://academicjournals.org/proceeding/WANNPRES/article-full-text-pdf/E78B526

Effect of Synsepalum Dulcificum Extract on Oxidative Stress and hepatotoxicity indices:

https://miraburst.com/wp-content/uploads/2020/01/EFFECT-OF-SYNSEPALUM-DULCIFICUM-BERRY-EXTRACT-ON-OXIDATIVE-STRESS-AND-HEPATOTOXICITY-INDICES-FOLLOW.pdf