Clinical Research
Miracle berries and their active substance, miraculin, have both been thoroughly used in clinical research with positive results. We have posted a sampling of the available research here, and we invite you to keep an eye on this page for more articles coming soon.
Cancer Related Research
“Efficacy and Safety of Habitual Consumption of a Food Supplement Containing Miraculin in Malnourished Cancer Patients: the CLINMIR Pilot Study” https://www.researchgate.net/publication/380781713_Efficacy_and_Safety_of_Habitual_Consumption_of_a_Food_Supplement_Containing_Miraculin_in_Malnourished_Cancer_Patients_the_CLINMIR_Pilot_Study
The regular consumption of a food supplement containing miraculin can contribute to reducing biomarkers of inflammation and cachexia in malnourished patients with cancer and taste disorders. https://www.researchgate.net/publication/381673434_The_Regular_Consumption_of_a_Food_Supplement_Containing_Miraculin_Can_Contribute_to_Reducing_Biomarkers_of_Inflammation_and_Cachexia_in_Malnourished_Patients_with_Cancer_and_Taste_Disorders_The_CLINMIR
Effects of novel food rich in miraculin on the intestinal microbiome of malnourished patients with cancer and dysgeusia https://www.researchgate.net/publication/383316357_Effect_of_a_novel_food_rich_in_miraculin_on_the_intestinal_microbiome_of_malnourished_patients_with_cancer_and_dysgeusia
Effects of novel food rich in miraculin on the oral microbiome of malnourished oncologic patients with dysgeusia https://www.researchgate.net/publication/382307155_Effect_of_a_novel_food_rich_in_miraculin_on_the_oral_microbiome_of_malnourished_oncologic_patients_with_dysgeusia
“Miracle Berry as a Potential Supplement in the Control of Metabolic Risk Factors in Cancer” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7765360/
“Synsepalum dulcificum extracts exhibit cytotoxic activity on human colorectal cancer cells and upregulate c-fos and c-jun early apoptotic gene expression”:
https://www.researchgate.net/publication/322068964_Synsepalum_dulcificum_extracts_exhibit_cytotoxic_activity_on_human_colorectal_cancer_cells_and_upregulate_c-fos_and_c-jun_early_apoptotic_gene_expression
“Effect of Regular Consumption of a Miraculin-Based Food Supplement on Taste Perception and Nutritional Status in Malnourished Cancer Patients: the CLINMIR Pilot Study” https://www.medrxiv.org/content/10.1101/2024.05.15.24307453v1.full
“Anti-Angiogenesis and Anticancer Activities”: https://www.researchgate.net/publication/362696862_Identification_of_phenolics_from_miracle_berry_Synsepalum_dulcificum_leaf_extract_and_its_antiangiogenesis_and_anticancer_activities
“Evaluation of the antimicrobial and anticancer properties of the fruits of Synsepalum dulcificum (Sapotaceae)” https://miraburst.com/wp-content/uploads/2024/05/Evaluation_of_the_antimicrobial_and_anti.pdf
“Biological Activities of Miracle Berry Supercritical Extracts as Metabolic Regulators in Chronic Diseases” https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10138767/
“Treatment of Taste Alterations in Chemotherapy Patients Using the ‘Miracle Fruit’”: Preliminary Analysis of a Pilot Study.” American Society of Clinical Oncology (ASCO):
http://meetinglibrary.asco.org/content/51247-74
“Pilot Study of ‘Miracle Fruit’ to Improve
Food Palatability for Patients Receiving Chemotherapy.” U.S. National Library of Medicine National Institutes of Health: http://www.ncbi.nlm.nih.gov/pubmed/23022943
Diabetes Related Research
“Anti-Diabetic Properties of Synsepalum dulcificum and Its Potential Inclusion in Functional Yogurt”:
https://www.researchgate.net/publication/339197762_Anti-diabetic_properties_of_Synsepalum_dulcificum_and_its_potential_inclusion_in_functional_yogurt
“Improvement of Insulin Resistance by Miracle Fruit (Synsepalum dulcificum) in Fructose-Rich Chow-Fed Rats.” U.S. National Library of Medicine National Institutes of Health:
http://www.ncbi.nlm.nih.gov/pubmed/16941611
Modulatory Effects of Miracle Fruit Ethanolic Extracts on Glucose Uptake Through the Insulin Signaling Pathway in C2C12 Mouse Myotubes Cells”: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418466/
“Antihyperglycemic and hepatoprotective properties of miracle fruit (Synsepalum dulcificum) compared to aspartame in alloxan-induced diabetic mice” https://www.researchgate.net/publication/344151973_Antihyperglycemic_and_hepatoprotective_properties_of_miracle_fruit_Synsepalum_dulcificum_compared_to_aspartame_in_alloxan-induced_diabetic_mice
“Anti-Diabetic Effect of the Leaf Extracts of the Miracle Berry”: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5747512/
“Antidiabetic Potential of the Leaf Extract of Miracle Berry Plant in Type 2 Diabetes”:
https://www.ncbi.nlm.nih.gov/pubmed/31374224“
As a Taste Modifier
“Taste Modification for Novel Foods”: https://www.researchgate.net/publication/342448332_Taste_Modification_Using_Miracle_Berry_Synsepalum_dulcificum_A_Dynamic_Approach_for_Novel_Foods
“Positive improvement in palatability of metabolic formula with the use of miraculin protein in patients with inborn errors of metabolism and healthy adults” https://miraburst.com/wp-content/uploads/2024/11/Positive_improvement_in_palatability_of.pdf
“The Miracle Berry and Miraculin: A Review”: http://miracleberryandmiraculin.wordpress.com/2014/07/27/the-miracle-berry-and-miraculin-a-review/
“The Miracle Fruit: An Undergraduate Laboratory Exercise in Taste Sensation and Perception”: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105965/
Phytochemicals, Nutritionals, and Antioxidant Properties of the Miracle Berry
“Chemical Constituents and Their Antioxidant Activities”: https://www.researchgate.net/publication/346056975_Chemical_constituents_and_their_antioxidant_activities_from_the_leaves_of_Synsepalum_dulcificum
“Physicochemical Characterisation of Polysaccharides from the Seeds and Leaves of Miracle Fruit (Synsepalum dulcificum) and Their Antioxidant and α -Glucosidase Inhibitory Activities In Vitro”:
https://www.researchgate.net/publication/315908404_Physicochemical_Characterisation_of_Polysaccharides_from_the_Seeds_and_Leaves_of_Miracle_Fruit_Synsepalum_dulcificum_and_Their_Antioxidant_and_a_-Glucosidase_Inhibitory_Activities_In_Vitro
“Phytochemicals, Nutritionals, and Antioxidant Properties of the Miracle Berry”: https://www.researchgate.net/publication/299418843_Phytochemicals_nutritionals_and_antioxidant_properties_of_miracle_fruit_Synsepalum_dulcificum
“Phytochemicals, Antinutrient, and Amino Acid Composition of the Miracle Berry”:
http://www.iosrjournals.org/iosr-jpbs/papers/Vol9-issue2/Version-5/E09252529.pdf
“Amino Acid Profile and Oxidazable Vitamin Content of Miracle Fruit”:
https://onlinelibrary.wiley.com/doi/full/10.1002/fsn3.213
“Proximate and Micronutrient Analysis of Miracle Fruit”: https://www.academia.edu/7914076/PROXIMATE_AND_MICRONUTRIENT_ANALYSES_OF_SYNSEPALUM_DULCIFICUM_PULP
“Potential Nutritional Values of Skin, Pulp, and Seed of the Miracle Fruit”: https://pdfs.semanticscholar.org/5ce4/919e7543d26bb35665fcf6dae1b265bdeafb.pdf
“Proximate, Anti-Nutritional, and Phytochemical Composition of the Yellow Variety of the Miracle Fruit”:
https://www.researchgate.net/publication/333802758_Proximate_Anti-Nutritional_and_Phytochemical_Composition_of_the_Yellow_Variety_of_the_Synsepalum_Dulcificum_Miracle_Fruit_Berry
“Nutritionals, Anti-Nutritional, and Phytochemical Profile of the Leaves and Fruit of the Miracle Fruit”:
https://miraburst.com/wp-content/uploads/2020/01/Nutritionals-Anti-Nutritional-and-Phytochemical-Profile-of-the-Leaves-and-Fruit-of-the-Miracle-Fruit.pdf
“Contents of Phenolics and Flavonoids and Antioxidant Activities in Skin, Pulp, and Seeds of Miracle Fruit.” U.S. National Library of Medicine National Institutes of Health:
http://www.ncbi.nlm.nih.gov/pubmed/21535817
“Antioxidant-Rich Phytochemicals in Miracle Berry (Synsepalum dulcificum) and Antioxidant Activity of Its Extracts.” U.S. National Library of Medicine National Institutes of Health:
http://www.ncbi.nlm.nih.gov/pubmed/24491731
Toxicology Analysis of the Miracle Berry
“Effects of Methanol Extract of Synsepalum Dulcificum Pulp on Some Biochemical Parameters in Albino Rats”: https://academicjournals.org/proceeding/WANNPRES/article-full-text-pdf/E78B526
“Effect of Synsepalum Dulcificum Extract on Oxidative Stress and Hepatotoxicity Indices”:
https://miraburst.com/wp-content/uploads/2020/01/EFFECT-OF-SYNSEPALUM-DULCIFICUM-BERRY-EXTRACT-ON-OXIDATIVE-STRESS-AND-HEPATOTOXICITY-INDICES-FOLLOW.pdf
Non-Allergic Properties
“Discarded Cross-Allergy Between Miracle Berry (Synsepalum dulcificum) and Peanut”: https://www.researchgate.net/publication/363905524_Discarded_cross-allergy_between_miracle_berry_Synsepalum_dulcificum_and_peanut
Other Health Benefits of the Miracle Berry
“Nutritional Benefits, Phytochemical Constituents, Ethnomedical Uses, and Biological Properties of the Miracle Fruit Plant”: https://www.researchgate.net/publication/348008847_Nutritional_benefits_phytochemical_constituents_ethnomedicinal_uses_and_biological_properties_of_Miracle_fruit_plant_Synsepalum_dulcificum_Shumach_Thonn_Daniell
“Influence of Miracle Berry Extract and Microencapsulated Lactococcus on the Antioxidant Activity and Probiotic Viability of Functional Yogurt”: https://www.researchgate.net/publication/344245651_Influence_of_miracle_fruit_Synsepalum_dulcificum_extract_and_microencapsulated_Lactococcus_lactis_Gh1_on_the_antioxidant_activity_and_probiotic_viability_of_functional_yogur
“Anti-Hyperuricaemic Effect of Miracle Berry – Ability of the Miracle Berry to Reduce Uric Acid in the Blood”: https://www.ncbi.nlm.nih.gov/pubmed/26821007
Who We Are
Since 2014, MiraBurst, founded by Dr. Emmanuel Asare, has proudly offered the world’s leading natural taste-modifying and taste-masking superfruit: the miracle berry. Whether you are a cancer survivor, cancer patient undergoing chemotherapy with or without taste-disturbances, diabetic or prediabetic, you can now enjoy all the health benefits of this unique superfruit in the form of our trademarked MiraBurst Mini Squares. Order today!